Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands
نویسندگان
چکیده
The synthesis of a small number bis(imino)anthracene derivatives is reported. They were evaluated via NMR for binding efficacy to the G-quadruplex-forming oligonucleotide sequence (TTGGGTT) and show activity against HeLa cancer cell line.
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ژورنال
عنوان ژورنال: RSC medicinal chemistry
سال: 2021
ISSN: ['2632-8682']
DOI: https://doi.org/10.1039/d0md00428f